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Introduction to Streamlined Oncology Tools
Watch Introduction Video

Streamlined Oncology Calculators & Survival Analysis

For clinical decision & research support.

Browse by Specialty

Master Calculators

Myeloma Master Panel (R2-ISS & Frailty)

Integrates Disease Biology (R2-ISS) and Patient Fitness (IMWG) for treatment selection.

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Master Calculators

Febrile Neutropenia Triage

Combined MASCC and CISNE scores for risk stratification.

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Master Calculators

Palliative Survival Prediction

Survival estimates using PaP and PPI scores.

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Master Calculators

Liver & HCC Master Panel

Simultaneous calculation of Child-Pugh, ALBI, MELD-Na, BCLC, HKLC, and Milan Criteria.

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Master Calculators

Lung Nodule Malignancy Risk Panel

Comparison of Mayo, Brock (PanCan), and Herder models for pulmonary nodules.

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Master Calculators

Prostate Cancer Risk Stratification (NCCN & CAPRA)

Unified assessment using NCCN Guidelines (v4.2024), CAPRA Score, and Epstein Criteria.

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Master Calculators

Renal Cell Carcinoma (RCC) Prognosis Panel

Combined IMDC (Heng) and MSKCC (Motzer) risk stratification for metastatic RCC.

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Master Calculators

Lymphoma (DLBCL) Prognosis Panel

Combined Classic IPI and NCCN-IPI for Diffuse Large B-Cell Lymphoma.

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Universal / General Oncology

ECOG Performance Status

Derives performance status from functional ability (Activity, Self-care, Confinement).

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Universal / General Oncology

Body Surface Area (BSA)

Calculates BSA using Du Bois or Mosteller formulas.

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Universal / General Oncology

Karnofsky Performance Status (KPS)

Functional assessment scale (0-100) determining patient ability to perform ordinary tasks.

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Universal / General Oncology

WHO Performance Status

World Health Organization Performance Status scale.

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Universal / General Oncology

TNM Staging Recorder (Universal)

A tool to record T, N, and M values. Note: Exact staging is site-specific.

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Universal / General Oncology

Charlson Comorbidity Index

Predicts 10-year mortality based on comorbid conditions and age.

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Universal / General Oncology

RMH Score (Phase I Trials)

Royal Marsden Hospital prognostic score for Phase I trial patients.

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Universal / General Oncology

Khorana Score (VTE Risk)

Predicts risk of Venous Thromboembolism in cancer patients starting chemotherapy.

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Universal / General Oncology

CUPI Score (Cancer of Unknown Primary)

Prognostic index for carcinoma of unknown primary site.

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Head & Neck / NPC

EBV-DNA Prognostic Score (NPC)

Refines NPC prognosis using TNM stage and pre-treatment EBV DNA.

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Upper GI & Pancreatic

MSKCC Pancreatic Cancer Nomogram

Predicts survival after resection of pancreatic adenocarcinoma.

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Upper GI & Pancreatic

Fistula Risk Score (FRS)

Predicts Pancreatic Fistula (CR-POPF) risk after pancreaticoduodenectomy.

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Upper GI & Pancreatic

MSKCC Gastric Cancer Nomogram

Predicts survival after R0 resection for gastric cancer.

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Upper GI & Pancreatic

JGCA Risk Classifier (EGC Curability)

Determines curability of Early Gastric Cancer (EGC) by ESD.

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GI, GIST & Peritoneal

Modified Glasgow Prognostic Score (mGPS)

Prognostic score based on systemic inflammation (CRP and Albumin).

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GI, GIST & Peritoneal

Fong Clinical Risk Score (CRS)

Predicts recurrence after resection of colorectal liver metastases.

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GI, GIST & Peritoneal

Peritoneal Carcinomatosis Index (PCI)

Quantifies tumor burden in the peritoneal cavity (Sugarbaker).

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GI, GIST & Peritoneal

NIH GIST Risk (Miettinen)

Predicts recurrence risk for GIST based on size and mitotic count.

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GI, GIST & Peritoneal

AFIP GIST Risk (Miettinen)

Refined GIST risk assessment including tumor location.

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GI, GIST & Peritoneal

Oncotype DX® Colon Recurrence Score

Predicts recurrence risk in Stage II/III colon cancer.

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GI, GIST & Peritoneal

Stage II Colon Cancer Risk Assessment

Identifies high-risk features for adjuvant chemotherapy.

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GI, GIST & Peritoneal

PSDSS (Prostate Cancer-Specific Survival)

Peritoneal Surface Disease Severity Score (Pelz/Sugarbaker).

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Lung Cancer & IO

GRIm Score

Gustave Roussy Immune Score for immunotherapy prognosis.

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Lung Cancer & IO

LIPI Score (Lung Immune)

Lung Immune Prognostic Index for NSCLC immunotherapy outcomes.

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Lung Cancer & IO

Lung-RADS™ v2022

ACR Lung Imaging Reporting and Data System for screening CTs.

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Lung & Thoracic Oncology

Small Cell Lung Cancer Staging (VALSG)

Veterans Administration Lung Study Group (VALSG) staging for SCLC.

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Lung & Thoracic Oncology

Solitary Pulmonary Nodule Malignancy Risk (Mayo)

Estimates probability of malignancy in a solitary pulmonary nodule (SPN).

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Lung & Thoracic Oncology

Herder Model (Pulmonary Nodule)

Malignancy risk for pulmonary nodules incorporating PET-CT results.

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Lung & Thoracic Oncology

Brock (PanCan) Nodule Risk

Estimates malignancy probability in pulmonary nodules (McWilliams/PanCan).

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Lung & Thoracic Oncology

PLCOm2012 Lung Cancer Risk

Predicts 6-year risk of lung cancer in ever-smokers.

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Lung & Thoracic Oncology

Masaoka-Koga Staging (Thymoma)

Standard staging system for Thymic Malignancies.

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Lung & Thoracic Oncology

Mesothelioma EORTC Prognostic Index

Predicts survival in Malignant Pleural Mesothelioma (MPM).

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Lung & Thoracic Oncology

Mesothelioma CALGB Score

Cancer and Leukemia Group B (CALGB) prognostic scoring.

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Neuro-Oncology

WHO CNS Tumor Grade (2021)

Grading system for Central Nervous System tumors.

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Neuro-Oncology

RPA (Brain Metastases)

RTOG Recursive Partitioning Analysis for brain mets survival.

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Neuro-Oncology

GPA (Graded Prognostic Assessment)

Original GPA score for brain metastases prognosis.

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Neuro-Oncology

Diagnosis-Specific GPA (Brain Mets)

Updated GPA scores by primary site (Lung, Breast, Melanoma, Renal, GI).

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Bone & Spine Metastases

Tokuhashi Score (Spine Mets)

Predicts survival for metastatic spine tumors to guide surgery.

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Bone & Spine Metastases

Tomita Score (Spine Mets)

Prognostic scoring for surgical strategy in spinal metastases.

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Bone & Spine Metastases

SINS (Spinal Instability)

Spinal Instability Neoplastic Score for tumor-related instability.

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Bone & Spine Metastases

NESMS (Epidural Spinal Cord)

New England Spinal Metastasis Score for post-op survival.

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Bone & Spine Metastases

Mirels Score (Fracture Risk)

Predicts risk of pathologic fracture in long bones.

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Bone & Spine Metastases

Bauer Score (Bone Mets)

Prognostic score for metastatic spine surgery survival.

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Bone & Spine Metastases

Katagiri Score (Bone Mets)

Prognostic score for patients with bone metastases.

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Sarcoma

FNCLCC Grade (Soft Tissue Sarcoma)

Histologic grading of soft tissue sarcomas (French Federation).

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Sarcoma

Enneking Staging (Bone/Sarcoma)

Surgical staging system for musculoskeletal sarcomas.

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Histiocytic Disorders

HLH-2004 Diagnostic Criteria

Diagnostic criteria for Hemophagocytic Lymphohistiocytosis.

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Histiocytic Disorders

HScore for HLH

Estimates probability of Hemophagocytic Lymphohistiocytosis (HLH).

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Histiocytic Disorders

LCH Risk Organ Classification

Stratifies LCH into Single/Multi-system and Risk Organ status.

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Histiocytic Disorders

Ann Arbor Staging (Histiocytic Sarcoma)

Anatomic staging analogous to lymphoma for Histiocytic Sarcoma.

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Endocrine Tumors

Weiss Score (Adrenal)

Differentiates benign adrenocortical adenoma from carcinoma (ACC).

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Endocrine Tumors

PASS Score (Pheochromocytoma)

Pheochromocytoma of the Adrenal Gland Scaled Score.

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Endocrine Tumors

NET Grade / WHO 2019

Histological grading of Neuroendocrine Tumors (NETs).

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Supportive Care & Emergencies

MASCC Risk Index

Identifies low-risk patients with febrile neutropenia.

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Supportive Care & Emergencies

CARG Toxicity Score (Geriatric)

Predicts Grade 3-5 chemotherapy toxicity in older adults (≥65y).

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Supportive Care & Emergencies

G8 Screening Tool

Screening tool to identify older cancer patients requiring full geriatric assessment.

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Supportive Care & Emergencies

CISNE Score (Febrile Neutropenia)

Clinical Index of Stable Febrile Neutropenia.

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Pain & Palliative

Opioid Rotation & OME Calculator

Evidence-based conversion with NCCN safety pearls for cancer pain rotation and breakthrough dosing.

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Pain & Palliative

ESAS-r Symptom Score

Edmonton Symptom Assessment System (Revised) for symptom burden.

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Pain & Palliative

PaP Score (Palliative Prognosis)

Predicts 30-day survival in palliative care patients.

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Pain & Palliative

Palliative Prognostic Index (PPI)

Predicts survival (weeks vs months) in terminal cancer.

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Hematology

NCCN-IPI (Lymphoma)

Enhanced prognostic index for Diffuse Large B-Cell Lymphoma.

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Hematology

CLL-IPI

International Prognostic Index for Chronic Lymphocytic Leukemia.

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Hematology

MIPI (Mantle Cell Lymphoma)

Mantle Cell Lymphoma International Prognostic Index.

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Hematology

IPS (Hodgkin Lymphoma)

Hasenclever International Prognostic Score for Advanced HL.

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Hematology

IPS-7 (Adult Hodgkin Lymphoma)

Prognostic score for advanced-stage (III-IV) HL in adults.

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Hematology

CHIPS (Childhood Hodgkin Score)

The standard prognostic score for pediatric and adolescent Hodgkin Lymphoma.

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Hematology

DIPSS (Myelofibrosis)

Dynamic International Prognostic Scoring System for Primary Myelofibrosis.

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Hematology

DIPSS-Plus (Myelofibrosis)

Refined prognosis for Primary Myelofibrosis (incorporates karyotype).

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Hematology

IPSSWM (Waldenström)

International Prognostic Scoring System for Waldenström Macroglobulinemia.

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Hematology

IPSET-Thrombosis (Essential Thrombocythemia)

Predicts thrombosis risk in Essential Thrombocythemia (ET).

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Hematology

ELTS Score (CML)

EUTOS Long-Term Survival score for CML.

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Hematology

SANZ Risk Score (APL)

Stratifies risk in Acute Promyelocytic Leukemia (APL).

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Hematology

HCT-CI (Transplant Risk)

Hematopoietic Cell Transplantation-Specific Comorbidity Index.

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Hematology

R-ISS (Multiple Myeloma)

Revised International Staging System for Multiple Myeloma.

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Hematology

FLIPI (Follicular Lymphoma)

Follicular Lymphoma International Prognostic Index.

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Hematology

IPSS-R for MDS

Revised International Prognostic Scoring System for Myelodysplastic Syndromes.

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Hematology

International Prognostic Index (IPI)

International Prognostic Index for DLBCL.

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Liver / HCC

ALBI Score

Albumin-Bilirubin Grade for Hepatocellular Carcinoma (HCC) risk assessment.

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Liver / HCC

ALBI-T Score

Tumor-integrated ALBI grade for HCC prognosis.

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Liver / HCC

BCLC Staging System (2022 Update)

Barcelona Clinic Liver Cancer staging (2022 update).

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Liver / HCC

HKLC Staging System

Hong Kong Liver Cancer staging for treatment stratification.

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Liver / HCC

CNLC Staging (China)

China Liver Cancer staging system.

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Liver / HCC

JIS Score (Japan Integrated Staging)

Combines Child-Pugh grade and Japanese TNM stage.

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Liver / HCC

Child-Pugh Score

Estimates severity of cirrhosis and expected survival rate.

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Liver / HCC

MELD Score

Model for End-Stage Liver Disease (Original) for liver transplant prioritization.

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Liver / HCC

Milan Criteria

Determines eligibility for liver transplantation in HCC patients.

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Liver / HCC

CLIP Score

Cancer of the Liver Italian Program score for HCC prognosis.

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Liver / HCC

LI-RADS® v2018 (CT/MRI)

Standardized reporting for liver lesions in at-risk patients.

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Kidney / Renal

IMDC (Heng) Risk Score

Prognostic model for metastatic Renal Cell Carcinoma (mRCC).

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Kidney / Renal

MSKCC (Motzer) Score

Prognostic model for metastatic Renal Cell Carcinoma (mRCC).

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Kidney / Renal

Leibovich Score (RCC)

Predicts metastasis-free survival for clear cell RCC after nephrectomy.

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Kidney / Renal

SSIGN Score (Mayo)

Stage, Size, Grade, and Necrosis score for RCC prognosis.

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Kidney / Renal

UISS (UCLA Integrated Staging)

Prognostic system for localized Renal Cell Carcinoma.

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Breast Cancer

BI-RADS Score (Breast)

Breast Imaging-Reporting and Data System.

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Breast Cancer

Nottingham Prognostic Index (NPI)

Prognostic index for invasive breast cancer.

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Breast Cancer

MSKCC DCIS Nomogram

Estimates local recurrence risk after breast-conserving surgery for DCIS.

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Breast Cancer

Van Nuys Prognostic Index (USC-VNPI)

Prognostic index for Ductal Carcinoma In Situ (DCIS).

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Breast Cancer

CPS+EG Score

Estimates prognosis after neoadjuvant chemotherapy.

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Breast Cancer

Allred Score for ER/PR

Standard scoring system for Estrogen (ER) and Progesterone (PR) hormone receptors.

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Breast Cancer

Magee Equation (Est. Oncotype DX®)

Estimates the Oncotype DX® Recurrence Score using standard pathology data.

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Breast Cancer

AJCC Prognostic Stage (Breast)

Anatomic TNM staging with prognostic biomarker recording.

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Breast Cancer

Residual Cancer Burden (RCB)

Quantifies residual disease after neoadjuvant chemotherapy.

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Breast Cancer

PREDICT Breast (Prognostic Index)

Estimates prognosis using the PREDICT v2.1/2.2 model parameters.

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Breast Cancer

Gail Model (Relative Risk)

Estimates relative risk of developing invasive breast cancer.

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Breast Cancer

Oncotype DX Interpreter

Interprets Recurrence Score (RS) based on TAILORx and RxPONDER trials.

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Breast Cancer

MammaPrint Interpreter

Interprets MammaPrint (70-gene signature) results (High vs Low Risk).

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Breast Cancer

Prosigna / PAM50 Interpreter

Interprets PAM50 ROR Score for recurrence risk.

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Breast Cancer

EndoPredict (EPclin) Interpreter

Interprets EPclin Score for early and late recurrence risk.

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Breast Cancer

Breast Cancer Index (BCI)

Predicts benefit from Extended Endocrine Therapy (EET).

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Prostate Cancer

D'Amico Risk Classification

Stratifies prostate cancer recurrence risk (Low, Intermediate, High).

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Prostate Cancer

Epstein Criteria (Insignificant Cancer)

Predicts clinically insignificant prostate cancer suitable for Active Surveillance.

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Prostate Cancer

PI-RADS™ v2.1 (Prostate MRI)

Prostate Imaging Reporting and Data System for MRI assessment.

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Prostate Cancer

Gleason Score & ISUP Grade

Converts Gleason patterns into ISUP Grade Groups (1-5).

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Prostate Cancer

CAPRA Score

Cancer of the Prostate Risk Assessment (UCSF) score.

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Prostate Cancer

CAPRA-S Score (Post-Surgical)

Predicts recurrence after radical prostatectomy (Pathologic data).

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Prostate Cancer

Decipher® Prostate Risk

Interprets genomic classifier score for metastasis risk.

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Prostate Cancer

Prolaris® (CCP Score)

Assess tumor aggressiveness via Cell Cycle Progression (CCP) genes.

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Prostate Cancer

Oncotype DX® GPS (Prostate)

Genomic Prostate Score (GPS) for tumor aggressiveness.

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Prostate Cancer

ProMark® Proteomic Score

Proteomic prediction of aggressive prostate cancer behavior.

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Bladder / Urothelial

EORTC Risk Tables (NMIBC)

Predicts recurrence and progression in Non-Muscle Invasive Bladder Cancer.

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Bladder / Urothelial

CUETO Risk Score (BCG-Treated)

Predicts recurrence and progression in NMIBC patients treated with BCG.

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Bladder / Urothelial

EAU NMIBC Risk Stratification (2024)

Current EAU guideline risk groups (Low, Intermediate, High, Very High).

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Testicular & Germ Cell Tumors

IGCCCG Risk Classification (2021 Update)

Prognostic staging for metastatic germ cell tumors (Modern Era).

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Testicular & Germ Cell Tumors

MSKCC Stage I NSGCT Nomogram

Predicts occult disease in Clinical Stage I Non-Seminoma.

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Gynecologic Oncology

FIGO GTN Risk Score

Stratifies risk for Gestational Trophoblastic Neoplasia.

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Gynecologic Oncology

RMI (Risk of Malignancy Index)

Estimates malignancy risk in adnexal masses.

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Gynecologic Oncology

ROMA Score (Ovarian)

Risk of Ovarian Malignancy Algorithm (HE4 + CA125).

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Gynecologic Oncology

AGO Score (DESKTOP)

Predicts resectability in recurrent ovarian cancer (Secondary Cytoreduction).

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Gynecologic Oncology

iMODEL (Ovarian Recurrence)

Predicts complete resection at secondary cytoreduction.

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Gynecologic Oncology

O-RADS™ (Ultrasound)

Ovarian-Adnexal Reporting and Data System (ACR v2022).

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Gynecologic Oncology

ESGO/ESTRO/ESP Endometrial Risk (2021)

Risk stratification for Endometrial Cancer (2021 Guidelines).

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Gynecologic Oncology

Mayo Criteria (Endometrial)

Predicts lymph node metastasis in endometrial cancer (surgical staging).

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Gynecologic Oncology

Sedlis Criteria (Cervical)

Identifies intermediate risk factors for adjuvant radiation in cervical cancer.

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Gynecologic Oncology

Moore Criteria (Advanced Cervical)

Prognostic factors for recurrent/metastatic cervical cancer (GOG 110/169/179).

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Skin Cancer

Sentinel Lymph Node Risk (Melanoma)

Predicts risk of sentinel lymph node metastasis in thin/intermediate melanoma.

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Thyroid Cancer

MACIS Score (Thyroid)

Prognostic score for Papillary Thyroid Carcinoma (PTC).

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Thyroid Cancer

ATA Risk Stratification (Thyroid)

Predicts risk of recurrence in Differentiated Thyroid Cancer (DTC).

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About OncoToolkit: Your Comprehensive Oncology Calculator Resource

OncoToolkit provides healthcare professionals with a comprehensive suite of evidence-based oncology calculators, staging systems, and prognostic tools. Our platform supports clinical decision-making across all major cancer types, from initial diagnosis through treatment planning and follow-up care.

Comprehensive Cancer Staging & Prognosis Tools

Access validated scoring systems including ECOG and Karnofsky Performance Status for functional assessment, Child-Pugh and ALBI scores for liver function evaluation, and tumor-specific staging calculators following AJCC/UICC guidelines. Our tools cover breast cancer (Oncotype DX, NPI), prostate cancer (Gleason, CAPRA), lung cancer (TNM staging, GPA), and many more.

Treatment Decision Support

Make informed treatment decisions with calculators designed to assess treatment eligibility, predict response, and evaluate toxicity risk. From chemotherapy dosing based on BSA calculations to immunotherapy eligibility assessment, our tools help optimize patient outcomes while minimizing adverse events.

Evidence-Based Clinical Tools

Every calculator on OncoToolkit is based on peer-reviewed research and validated in clinical practice. We provide transparent methodology with references to original publications, ensuring you understand the evidence behind each tool. Explore our oncology glossary for terminology definitions and video tutorials about how to use this app.

OncoToolkit is for educational and clinical decision support purposes only. Always verify results with current clinical guidelines and institutional protocols.