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Breast Cancer Index (BCI)
Clinical Context & Background
The Breast Cancer Index (BCI) reports two results: the BCI Prognostic Score (risk of late distant recurrence) and the BCI Predictive (H/I) Ratio (likelihood of benefit from extended endocrine therapy beyond 5 years). It is the only test guideline-endorsed specifically for the EET decision.
Formula Logic
H/I Ratio Interpretation.Reference Data
| H/I Ratio | Predictive Result | Recommendation |
|---|---|---|
| High | High Likelihood of Benefit | Extend Endocrine Therapy to 10 years |
| Low | Low Likelihood of Benefit | Stop Endocrine Therapy at 5 years (unless high clinical risk) |
Evidence-based oncology decision support. Verify with clinical guidelines.