The IMDC criteria stratify metastatic renal cell carcinoma patients into favourable, intermediate, or poor risk groups using six clinical and laboratory factors, guiding first-line systemic therapy selection.

Evidence-based context for fast calculator use

Purpose:

Risk-stratify metastatic RCC patients for first-line treatment selection

Population:

Patients with metastatic renal cell carcinoma initiating systemic therapy

Factors:

KPS <80%, Time from diagnosis to treatment <1 year, Haemoglobin below normal, Corrected calcium above normal, Neutrophils above normal, Platelets above normal

Reference:

Heng et al., JCO 2009