Clinical calculator summary
Oncotype DX Colon Recurrence Score Report Interpreter
Clinical calculator summary
Oncotype DX Colon Recurrence Score Report Interpreter
This route accepts only a final externally generated Exact Sciences proprietary 12-gene colon Recurrence Score.
Evidence-based context for fast calculator use
- Purpose:
- Strictly interprets a final Exact Sciences Oncotype DX Colon Recurrence Score using the prespecified QUASAR/NSABP C-07 score groups and supported report populations.
- Population:
- patients with the specific gastrointestinal, stromal, colorectal, or peritoneal disease context described by the model
- Factors:
- Final Exact Sciences Recurrence Score, Assay Report Population
Oncotype DX Colon Recurrence Score Report Interpreter
Enter the final report integer from 0 through 100; this calculator does not derive or estimate the assay score.
Clinical Context & Background
Final reported integer score identity lookup: 0-29 Low; 30-40 Intermediate; 41-100 High. No rounding, assay calculation, percentage estimation, or treatment recommendation.Reference Data
| Final reported score | Prespecified score group | Report marker |
|---|---|---|
| 0-29 | Low | Stage III A/B: score <30 is in lower-risk shading |
| 30-40 | Intermediate | No separate Stage II/III report shading marker |
| 41-100 | High | Stage II pMMR: score >=41 is in higher-risk shading |
Clinical Workflow
Use, Interpret, And Continue The Patient Pathway
Expand for workflow guidance, limitations, examples, and related next steps.
Clinical Workflow
Use, Interpret, And Continue The Patient Pathway
Expand for workflow guidance, limitations, examples, and related next steps.
When To Use
- Use Oncotype DX Colon Recurrence Score Report Interpreter when strictly interprets a final Exact Sciences Oncotype DX Colon Recurrence Score using the prespecified QUASAR/NSABP C-07 score groups and supported report populations.
- Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.
How To Interpret
- Interpret the displayed result using the calculator-specific formula and reference table, spanning 0-29 through 41-100.
- A boundary result should prompt input verification and clinical review rather than false precision.
What To Do Next
- Confirm primary site, histology, stage, surgery status, systemic-treatment timing, and disease-specific guideline before applying the result.
- Document the inputs, result, timing, and clinical context so the assessment can be reproduced.
Limitations
- Do not transfer thresholds across colorectal, GIST, gastric, appendiceal, and other peritoneal malignancies.
- The result supports clinician judgment and does not independently determine treatment.
Validated Population
patients with the specific gastrointestinal, stromal, colorectal, or peritoneal disease context described by the model
How to apply this result
For a representative case, verify Final Exact Sciences Recurrence Score, Assay Report Population, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.
Calculation verification history
Verified
Calculation verification history
Verified: Production browser revalidation
- Three source-backed Oncotype DX Colon cases passed through visible production controls at scores 0, 30, and 41 across Low, Intermediate, and High score groups.
- The unsupported generic risk gauge was absent; no unexpected N/A, literal undefined value, stale control, or browser-console error was observed.
Case-level evidence is retained in validation/browser-revalidation/oncotype-colon-2026-08-03.json.
: Local browser remediation
- All classified Oncotype DX Colon results now explicitly suppress the shared risk gauge so proprietary Low, Intermediate, and High score groups are not relabeled as patient risk bands.
- Ten source-backed cases passed through visible local browser controls across 11 submissions, covering exact group transitions, Stage II/III report markers, outside scope, required-field validation, and reset/repeat behavior.
- The existing calculator-specific audit passed 760/760. Production status remains open until this commit is deployed and the public route is revalidated.
Local case-level remediation evidence is retained in validation/browser-production/oncotype-colon.local-remediation.json.
: Production browser validation
- Ten source-backed cases were exercised on the public production route through visible browser controls; 2/10 case records passed their expected-versus-observed assertions across 11 visible submissions.
- Overall browser status: failed-ui-and-console. high: Every classified result displayed the shared `Low Risk / Intermediate / High Risk` gauge even though the supported output is only a Low, Intermediate, or High proprietary score group and the interpreter explicitly does not estimate individualized recurrence risk. | medium: Production emitted minified React error #418 during route loads/reloads used by this run.
- Case-level inputs, expected and observed results, reset/repeat behavior, failure reproductions, and console evidence are retained in the production-browser evidence record.
Case-level production evidence is retained in validation/browser-production/oncotype-colon.json.
: Input workflow simplified and revalidated
- Reduced the public form to result-, branch-, unit-, and applicability-changing inputs; removed or consolidated non-scoring, administrative, and duplicate questions.
- Preserved the verified calculation or report-interpretation logic, thresholds, model version, component logic, and supported result pathways behind strict deterministic adapters.
- Passed the calculator-specific regression audit, adapter-parity and malformed-input checks, the 144-calculator input-quality audit, and the 43-calculator entry-burden audit.
: Full validation
- 760/760 independently expected source, exhaustive score-context, boundary, malformed-input, applicability, wording, trace, UI, immutability, linked-content, registry, inventory, report, history, and mirror assertions passed with zero group mismatch.
- This is source-to-code implementation verification, not independent clinical validation, individualized recurrence prediction, chemotherapy-benefit estimation, or treatment guidance.
: Calculation/input correction
- Reframed the permanent route as a final Exact Sciences reported-score interpreter using the prespecified QUASAR/NSABP C-07 Low, Intermediate, and High groups.
- Removed favorable defaults, Number coercion, decimals, approximate recurrence percentages, dMMR and unsupported-stage fallthrough, chemotherapy-benefit language, and regimen recommendations.
- Added exact report source/status, site, histology, T, nodes, resection, treatment, MMR, stage-population, trace, reset, linked-content, snapshot, and immutability gates.
Included in the current validation report.
Verification confirms the calculator implementation against the cited model; it is not independent clinical validation, regulatory approval, or medical advice.
Related Tools
Frequently Asked Questions
When should Oncotype DX Colon Recurrence Score Report Interpreter be used?
Use it for patients with the specific gastrointestinal, stromal, colorectal, or peritoneal disease context described by the model when all required inputs and the intended clinical setting are confirmed.
Can Oncotype DX Colon Recurrence Score Report Interpreter determine treatment by itself?
No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.
Evidence-based oncology decision support. Verify with clinical guidelines.