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Clinical calculator summary

Mayo Criteria (Endometrial)

The Mayo Clinic criteria identify patients with low-risk endometrial cancer who have a very low risk of lymph node metastasis.

Evidence-based context for fast calculator use

Purpose:
Mayo Criteria predict lymph node metastasis risk in endometrial cancer to guide surgical staging and lymphadenectomy decision-making.
Population:
patients undergoing ovarian, cervical, endometrial, or gestational-trophoblastic risk and staging assessment
Factors:
Tumor Grade, Myometrial Invasion, Tumor Diameter
Reference:
Mariani A, Webb MJ, Keeney GL, et al. Low-risk corpus cancer: is lymphadenectomy always necessary? Gynecol Oncol. 2000;78(1):13-19.
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Mayo Criteria (Endometrial)

Clinical Context & Background

The Mayo Clinic criteria identify patients with low-risk endometrial cancer who have a very low risk of lymph node metastasis. In these patients, systematic lymphadenectomy may be safely omitted to reduce morbidity (lymphedema).
Primary Source EvidenceMariani A, Webb MJ, Keeney GL, et al. Low-risk corpus cancer: is lymphadenectomy always necessary? Gynecol Oncol. 2000;78(1):13-19.
Formula Logic
Low risk if: Grade 1-2, Myometrial invasion ≤ 50%, Tumor size ≤ 2 cm.

Reference Data

CriteriaRisk of LN MetastasisRecommendation
Met All< 1%Lymphadenectomy may be omitted
Failed Any> 5-10%Lymphadenectomy (or SLN) recommended

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use Mayo Criteria (Endometrial) when mayo Criteria predict lymph node metastasis risk in endometrial cancer to guide surgical staging and lymphadenectomy decision-making.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning Met All through Failed Any.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Confirm organ site, pathology, menopausal or postoperative context, imaging, biomarker assay, and specialist referral pathway.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Adnexal-mass, cervical postoperative, endometrial, and ovarian cytoreduction models answer different clinical questions.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing ovarian, cervical, endometrial, or gestational-trophoblastic risk and staging assessment

How to apply this result

For a representative case, verify Tumor Grade, Myometrial Invasion, Tumor Diameter, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Gynecologic Oncology hubContinue to related calculators and clinical workflow resources.

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Frequently Asked Questions

When should Mayo Criteria (Endometrial) be used?

Use it for patients undergoing ovarian, cervical, endometrial, or gestational-trophoblastic risk and staging assessment when all required inputs and the intended clinical setting are confirmed.

Can Mayo Criteria (Endometrial) determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.