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Clinical calculator summary

Lung-RADS™ v2022

Lung-RADS™ is a quality assurance tool used to standardize lung cancer screening CT reporting, management recommendations, and data monitoring.

Evidence-based context for fast calculator use

Purpose:
Lung-RADS v2022 categorizes pulmonary nodules on screening CT to standardize lung cancer risk assessment and guide follow-up intervals.
Population:
patients undergoing lung cancer immunotherapy or prognostic assessment
Factors:
Most Suspicious Finding
Reference:
American College of Radiology (ACR). Lung-RADS® v2022 Assessment Categories.
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Lung-RADS™ v2022

Clinical Context & Background

Lung-RADS™ is a quality assurance tool used to standardize lung cancer screening CT reporting, management recommendations, and data monitoring. It categorizes findings based on nodule size, consistency, and growth.
Primary Source EvidenceAmerican College of Radiology (ACR). Lung-RADS® v2022 Assessment Categories.
Formula Logic
Classification based on worst finding.

Reference Data

CategoryDescriptionManagement
1NegativeContinue annual screening
2Benign AppearanceContinue annual screening
3Probably Benign6-month LDCT
4ASuspicious3-month LDCT or PET/CT
4BVery SuspiciousChest CT (contrast), PET/CT, or Tissue Sampling
4XCategory 3/4 with additional featuresChest CT, PET/CT, or Tissue Sampling

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use Lung-RADS™ v2022 when lung-RADS v2022 categorizes pulmonary nodules on screening CT to standardize lung cancer risk assessment and guide follow-up intervals.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning 1 through 4X.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Integrate the result with histology, molecular profile, stage, treatment line, imaging, and performance status.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Do not transfer an immunotherapy or laboratory prognostic score to an unvalidated treatment setting.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing lung cancer immunotherapy or prognostic assessment

How to apply this result

For a representative case, verify Most Suspicious Finding, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Lung Cancer & IO hubContinue to related calculators and clinical workflow resources.

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Frequently Asked Questions

When should Lung-RADS™ v2022 be used?

Use it for patients undergoing lung cancer immunotherapy or prognostic assessment when all required inputs and the intended clinical setting are confirmed.

Can Lung-RADS™ v2022 determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.