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AJCC Prognostic Stage (Breast)
Clinical Context & Background
The AJCC 8th Edition Breast Cancer Staging System incorporates biologic factors (Grade, ER, PR, HER2) alongside Anatomic TNM to determine the Prognostic Stage. This calculator determines the Anatomic Stage and records prognostic factors to help determining the final clinical or pathological prognostic stage.
Formula Logic
Anatomic Stage = T + N + M. Prognostic Stage modifies this based on biomarkers.Reference Data
| Anatomic Stage | TNM Criteria |
|---|---|
| Stage 0 | Tis N0 M0 |
| Stage IA | T1 N0 M0 |
| Stage IB | T0/1 N1mi M0 |
| Stage IIA | T0/1 N1 M0 or T2 N0 M0 |
| Stage IIB | T2 N1 M0 or T3 N0 M0 |
| Stage IIIA | T0-2 N2 M0 or T3 N1-2 M0 |
| Stage IIIB | T4 N0-2 M0 |
| Stage IIIC | Any T N3 M0 |
| Stage IV | Any T Any N M1 |
Evidence-based oncology decision support. Verify with clinical guidelines.