Saved Results

No results saved yet.

Enter a patient name and hit Save on a result.

Clinical calculator summary

LI-RADS® v2018 (CT/MRI)

The Liver Imaging Reporting and Data System (LI-RADS) assigns a category (LR-1 to LR-5) reflecting the probability of Hepatocellular Carcinoma (HCC).

Evidence-based context for fast calculator use

Purpose:
LI-RADS v2018 classifies liver observations on CT/MRI to estimate HCC probability and guide diagnostic workup in at-risk patients.
Population:
patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment
Factors:
Arterial Phase Hyperenhancement, Observation Size, Count of Major Features
Reference:
American College of Radiology (ACR). CT/MRI LI-RADS® v2018.
HomeLI-RADS® v2018 (CT/MRI)
Pin your most used calculators here by clicking the star in the dropdown.

LI-RADS® v2018 (CT/MRI)

Clinical Context & Background

The Liver Imaging Reporting and Data System (LI-RADS) assigns a category (LR-1 to LR-5) reflecting the probability of Hepatocellular Carcinoma (HCC). It applies to patients at high risk (cirrhosis, chronic HBV, or current/prior HCC). This calculator implements the CT/MRI Diagnostic Table.
Primary Source EvidenceAmerican College of Radiology (ACR). CT/MRI LI-RADS® v2018.
Formula Logic
Algorithm based on APHE, Size, Capsule, Washout, and Growth.

Reference Data

CategoryConceptProbability of HCC
LR-3Intermediate ProbabilityVariable
LR-4Probable HCCHigh
LR-5Definite HCC100% Specificity (approx)
LR-MProbably/Definitely Malignant (Not specific for HCC)High (includes Cholangiocarcinoma/Mets)

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use LI-RADS® v2018 (CT/MRI) when lI-RADS v2018 classifies liver observations on CT/MRI to estimate HCC probability and guide diagnostic workup in at-risk patients.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning LR-3 through LR-M.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Integrate liver reserve, portal hypertension, tumor burden, vascular invasion, extrahepatic disease, performance status, and transplant policy.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Liver function, HCC stage, imaging category, and transplant criteria are complementary but not interchangeable.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment

How to apply this result

For a representative case, verify Arterial Phase Hyperenhancement, Observation Size, Count of Major Features, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Liver / HCC hubContinue to related calculators and clinical workflow resources.

Share This Calculator

Share:

Related Tools

ALBI ScoreALBI-T ScoreBCLC Staging System (2022 Update)

Frequently Asked Questions

When should LI-RADS® v2018 (CT/MRI) be used?

Use it for patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment when all required inputs and the intended clinical setting are confirmed.

Can LI-RADS® v2018 (CT/MRI) determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.