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Clinical calculator summary

MSKCC Pancreatic Cancer Nomogram

The MSKCC (Brennan) Pancreatic Cancer Nomogram predicts disease-specific survival following resection (R0 or R1) of pancreatic ductal adenocarcinoma.

Evidence-based context for fast calculator use

Purpose:
MSKCC Pancreatic Nomogram estimates disease-specific survival after pancreatic adenocarcinoma resection to guide adjuvant treatment planning.
Population:
patients undergoing gastric or pancreatic cancer pathology, recurrence, or postoperative prognostic assessment
Factors:
Differentiation, Lymph Node Status, Resection Margin Status, Tumor Size, Presentation with Severe Back Pain?
Reference:
Brennan MF, Kattan MW, Klimstra D, Conlon K. Prognostic nomogram for patients undergoing resection for adenocarcinoma of the pancreas. Ann Surg. 2004;240(2):293-298.
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MSKCC Pancreatic Cancer Nomogram

Clinical Context & Background

The MSKCC (Brennan) Pancreatic Cancer Nomogram predicts disease-specific survival following resection (R0 or R1) of pancreatic ductal adenocarcinoma. It relies on differentiation, lymph node status, margin status, and tumor size.
Primary Source EvidenceBrennan MF, Kattan MW, Klimstra D, Conlon K. Prognostic nomogram for patients undergoing resection for adenocarcinoma of the pancreas. Ann Surg. 2004;240(2):293-298.
Formula Logic
Prognostic score based on Grade, Nodes, Margins, and Size.

Reference Data

Total PointsMedian Survival3-Year Survival
Low Risk (0-100)24 - 30 months35% - 45%
Intermediate (100-150)15 - 20 months20% - 30%
High Risk (> 150)10 - 14 months< 15%

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use MSKCC Pancreatic Cancer Nomogram when mSKCC Pancreatic Nomogram estimates disease-specific survival after pancreatic adenocarcinoma resection to guide adjuvant treatment planning.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning Low Risk (0-100) through High Risk (> 150).
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Confirm resection status, pathologic stage, nodal assessment, margins, histology, treatment timing, and whether the model is postoperative or preoperative.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Postoperative nomograms and fistula-risk tools answer different questions and are not treatment-selection rules.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing gastric or pancreatic cancer pathology, recurrence, or postoperative prognostic assessment

How to apply this result

For a representative case, verify Differentiation, Lymph Node Status, Resection Margin Status, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

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Frequently Asked Questions

When should MSKCC Pancreatic Cancer Nomogram be used?

Use it for patients undergoing gastric or pancreatic cancer pathology, recurrence, or postoperative prognostic assessment when all required inputs and the intended clinical setting are confirmed.

Can MSKCC Pancreatic Cancer Nomogram determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.