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MIPI (Mantle Cell Lymphoma)
years
U/L
U/L
x10⁹/L
Clinical Context & Background
The MIPI is the standard prognostic tool for patients with advanced stage Mantle Cell Lymphoma (MCL). It uses a formula based on continuous variables (Age, ECOG, LDH, WBC) to calculate a prognostic score.
Formula Logic
Score = [0.03535 x Age] + [0.6978 (if ECOG > 1)] + [1.367 x log10(LDH/ULN)] + [0.9393 x log10(WBC)]Reference Data
| Risk Group | MIPI Score | Median Survival (Historical) |
|---|---|---|
| Low Risk | < 5.7 | Not reached (5y OS 60%) |
| Intermediate Risk | 5.7 - 6.2 | 51 months |
| High Risk | ≥ 6.2 | 29 months |
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