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Ann Arbor Staging (Histiocytic Sarcoma)
Clinical Context & Background
Due to the rarity of Histiocytic Sarcoma and its lymphoid-like spread pattern, the Ann Arbor staging system (originally for lymphoma) is commonly used to describe the extent of disease and guide treatment (Localized vs. Disseminated).
Primary Source EvidenceNCCN Clinical Practice Guidelines in Oncology (NCCN GuidelinesĀ®) for Histiocytic Neoplasms.
Formula Logic
Stage I-IV based on nodal/extranodal sites and diaphragm.Reference Data
| Stage | Description |
|---|---|
| Stage I | Single node region or single extranodal site (IE) |
| Stage II | Two or more node regions same side of diaphragm |
| Stage III | Nodal regions on both sides of diaphragm |
| Stage IV | Disseminated extranodal involvement (Liver, Marrow, Lung) |
Evidence-based oncology decision support. Verify with clinical guidelines.