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MSKCC (Motzer) Score
Clinical Context & Background
The Memorial Sloan Kettering Cancer Center (MSKCC) or Motzer Score is a prognostic model used to risk-stratify patients with metastatic renal cell carcinoma (mRCC). Originally developed in the cytokine era, it remains a historical benchmark and is still used in some clinical trials and settings, though IMDC is often preferred for targeted therapy.
Formula Logic
Sum of 5 risk factors (1 point each).Reference Data
| Risk Group | Risk Factors | Median Overall Survival (Historical) |
|---|---|---|
| Favorable Risk | 0 | 30 months |
| Intermediate Risk | 1 - 2 | 14 months |
| Poor Risk | ≥ 3 | 5 months |
Evidence-based oncology decision support. Verify with clinical guidelines.