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Leibovich Score (RCC)
Clinical Context & Background
The Leibovich Score (2003) is a standard prognostic model for patients with non-metastatic clear cell renal cell carcinoma (ccRCC) who have undergone radical nephrectomy. It uses pathologic T-stage, N-stage, tumor size, nuclear grade, and necrosis to predict the risk of metastasis.
Formula Logic
Sum of points for pT, pN, Size, Grade, Necrosis.Reference Data
| Risk Group | Score | 5-Year Metastasis-Free Survival |
|---|---|---|
| Low Risk | 0 - 2 | 97% |
| Intermediate Risk | 3 - 5 | 81% |
| High Risk | ≥ 6 | 68% (Score 6) to < 20% (Score >10) |
Evidence-based oncology decision support. Verify with clinical guidelines.