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Clinical calculator summary

MSKCC DCIS Nomogram

The Memorial Sloan Kettering DCIS nomogram predicts the probability of local recurrence after breast-conserving surgery for ductal carcinoma in situ, using pathological and treatment variables.

Evidence-based context for fast calculator use

Purpose:
Estimate 5 and 10-year local recurrence risk after breast-conserving surgery for DCIS
Population:
Women with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery
Factors:
Age at diagnosis, Family history, Presentation method, Nuclear grade, Necrosis, Margin status, Number of excisions, Radiation therapy, Endocrine therapy
Reference:
Memorial Sloan Kettering Cancer Center
HomeMSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator
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MSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator

Clinical Context & Background

The Memorial Sloan Kettering Cancer Center (MSKCC) DCIS Nomogram predicts the 5-year and 10-year risk of ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery alone (without radiation). It helps identify low-risk patients who might safely omit radiation therapy.
Primary Source EvidenceRudloff U, Jacks LM, Goldberg JI, et al. Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ. J Clin Oncol. 2010;28(23):3762-3769.
Formula Logic
Multivariable model using Age, Family Hx, Presentation, Margins, Grade, Necrosis, and Number of Excisions.

Reference Data

Risk FactorImpact on Recurrence
Age < 40High Risk
Positive / Close MarginsHigh Risk
High Grade / NecrosisHigh Risk
Symptomatic PresentationHigh Risk

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use MSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator when calculate DCIS recurrence risk using the Memorial Sloan Kettering (MSKCC) nomogram. Estimate 5 and 10-year local recurrence probability after breast-conserving surgery for ductal carcinoma in situ.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning Age < 40 through Symptomatic Presentation.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Integrate the result with invasive versus in-situ status, stage, receptor biology, treatment timing, genomic testing, comorbidity, and patient goals.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Do not interchange screening-risk, DCIS, invasive prognosis, genomic, and post-neoadjuvant tools.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing breast cancer risk, staging, pathology, recurrence, or treatment-benefit assessment

How to apply this result

For a representative case, verify Age at Diagnosis, Family History, Method of Detection, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Breast Cancer hubContinue to related calculators and clinical workflow resources.

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Frequently Asked Questions

When should MSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator be used?

Use it for patients undergoing breast cancer risk, staging, pathology, recurrence, or treatment-benefit assessment when all required inputs and the intended clinical setting are confirmed.

Can MSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.