Saved Results

No results saved yet.

Enter a patient name and hit Save on a result.

HomeRPA (Brain Metastases)
Pin your most used calculators here by clicking the star in the dropdown.

RPA (Brain Metastases)

years

Clinical Context & Background

The Radiation Therapy Oncology Group (RTOG) Recursive Partitioning Analysis (RPA) classifies patients with brain metastases into three prognostic classes based on age, Karnofsky Performance Status (KPS), control of primary tumor, and presence of extracranial metastases.
Primary Source EvidenceGaspar L, et al. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys. 1997;37(4):745-751.
Formula Logic
Classification logic based on Age, KPS, Primary Control, and Extracranial Mets.

Reference Data

RPA ClassCriteriaMedian Survival
Class IAge < 65, KPS ≥ 70, Primary controlled, No extracranial mets7.1 months
Class IIAll others4.2 months
Class IIIKPS < 702.3 months

Share This Calculator

Share:

Related Tools

WHO CNS Tumor Grade (2021)GPA (Graded Prognostic Assessment)Diagnosis-Specific GPA (Brain Mets)

Evidence-based oncology decision support. Verify with clinical guidelines.