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Clinical calculator summary

CAPRA-S Score (Post-Surgical)

The CAPRA-S (Cancer of the Prostate Risk Assessment - Surgical) score is calculated after radical prostatectomy using pathological data.

Evidence-based context for fast calculator use

Purpose:
CAPRA-S score predicts biochemical recurrence after radical prostatectomy using pathologic data to guide adjuvant prostate cancer treatment.
Population:
patients undergoing prostate cancer diagnostic, pathologic, recurrence, or molecular-risk assessment
Factors:
Pre-operative PSA, Pathologic Gleason Score, Surgical Margins, Seminal Vesicle Invasion, Extracapsular Extension, Lymph Node Invasion
Reference:
Cooperberg MR, Hilton JF, Carroll PR. The CAPRA-S score: A straightforward tool for improved prediction of outcomes after radical prostatectomy. Cancer. 2011;117(22):5039-5046.
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CAPRA-S Score (Post-Surgical)

Clinical Context & Background

The CAPRA-S (Cancer of the Prostate Risk Assessment - Surgical) score is calculated after radical prostatectomy using pathological data. It improves upon the pre-operative CAPRA score by incorporating surgical margins, seminal vesicle invasion, and lymph node status to predict biochemical recurrence-free survival (BCR).
Primary Source EvidenceCooperberg MR, Hilton JF, Carroll PR. The CAPRA-S score: A straightforward tool for improved prediction of outcomes after radical prostatectomy. Cancer. 2011;117(22):5039-5046.
Formula Logic
Sum of points from Pre-op PSA, Pathologic Gleason, Margins, Seminal Vesicle Invasion, Extracapsular Extension, and Lymph Node Invasion.

Reference Data

Risk GroupCAPRA-S Score5-Year Recurrence-Free Survival
Low Risk0 - 291% - 96%
Intermediate Risk3 - 570% - 87%
High Risk6 - 128% - 50%

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use CAPRA-S Score (Post-Surgical) when cAPRA-S score predicts biochemical recurrence after radical prostatectomy using pathologic data to guide adjuvant prostate cancer treatment.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning Low Risk through High Risk.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Confirm biopsy versus prostatectomy setting, PSA timing, grade group, clinical/pathologic stage, imaging, life expectancy, and treatment history.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Diagnostic, post-prostatectomy, genomic, and recurrence tools must be used only at their intended decision point.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing prostate cancer diagnostic, pathologic, recurrence, or molecular-risk assessment

How to apply this result

For a representative case, verify Pre-operative PSA, Pathologic Gleason Score, Surgical Margins, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Prostate Cancer hubContinue to related calculators and clinical workflow resources.

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Frequently Asked Questions

When should CAPRA-S Score (Post-Surgical) be used?

Use it for patients undergoing prostate cancer diagnostic, pathologic, recurrence, or molecular-risk assessment when all required inputs and the intended clinical setting are confirmed.

Can CAPRA-S Score (Post-Surgical) determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.