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Introduction to Streamlined Oncology Tools
Watch Introduction Video

Streamlined Oncology Calculators & Survival Analysis

For clinical decision & research support.

Browse by Specialty

Master Calculators

Myeloma Master Panel (R2-ISS & Frailty)

Integrates Disease Biology (R2-ISS) and Patient Fitness (IMWG) for treatment selection.

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Master Calculators

Febrile Neutropenia Triage

Combined MASCC and CISNE scores for risk stratification.

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Master Calculators

Palliative Survival Prediction

Survival estimates using PaP and PPI scores.

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Master Calculators

Liver & HCC Master Panel

Simultaneous calculation of Child-Pugh, ALBI, MELD-Na, BCLC, HKLC, and Milan Criteria.

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Master Calculators

Lung Nodule Malignancy Risk Panel

Comparison of Mayo, Brock (PanCan), and Herder models for pulmonary nodules.

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Master Calculators

Prostate Cancer Risk Stratification (NCCN & CAPRA)

Unified assessment using NCCN Guidelines (v4.2024), CAPRA Score, and Epstein Criteria.

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Master Calculators

Renal Cell Carcinoma (RCC) Prognosis Panel

Combined IMDC (Heng) and MSKCC (Motzer) risk stratification for metastatic RCC.

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Master Calculators

Lymphoma (DLBCL) Prognosis Panel

Combined Classic IPI, NCCN-IPI, aaIPI, CNS-IPI, and R-IPI for Diffuse Large B-Cell Lymphoma.

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Universal / General Oncology

ECOG Performance Status

ECOG Performance Status quantifies functional capacity in cancer patients to determine treatment eligibility and dose modification needs.

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Universal / General Oncology

Body Surface Area (BSA)

Body Surface Area calculator computes BSA using Du Bois or Mosteller formulas to determine accurate chemotherapy dosing in oncology patients.

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Universal / General Oncology

Karnofsky Performance Status (KPS)

Karnofsky Performance Status scale (0-100) quantifies functional capacity in oncology patients to guide treatment eligibility and prognosis.

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Universal / General Oncology

WHO Performance Status

WHO Performance Status scale classifies cancer patient functional ability from fully active to disabled to guide chemotherapy dosing decisions.

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Universal / General Oncology

TNM Staging Recorder (Universal)

Universal TNM staging recorder documents tumor, node, and metastasis classifications for any cancer site per AJCC 8th edition guidelines.

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Universal / General Oncology

Charlson Comorbidity Index

Charlson Comorbidity Index estimates 10-year survival by scoring 17 comorbid conditions and age to stratify mortality risk for treatment planning.

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Universal / General Oncology

RMH Score (Phase I Trials)

Royal Marsden Hospital score stratifies advanced cancer patients using albumin, LDH, and metastatic sites to assess Phase I trial eligibility.

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Universal / General Oncology

Khorana Score (VTE Risk)

Khorana score predicts venous thromboembolism risk in cancer patients starting chemotherapy to guide thromboprophylaxis prescribing decisions.

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Universal / General Oncology

CUPI Score (Cancer of Unknown Primary)

CUPI score stratifies cancer of unknown primary into low- and high-risk groups using performance status, histology, and labs to guide therapy intensity.

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Head & Neck / NPC

EBV-DNA Prognostic Score (NPC)

EBV-DNA Prognostic Score integrates pre-treatment EBV DNA with TNM staging to stratify nasopharyngeal carcinoma survival and guide therapy.

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Upper GI & Pancreatic

MSKCC Pancreatic Cancer Nomogram

MSKCC Pancreatic Nomogram estimates disease-specific survival after pancreatic adenocarcinoma resection to guide adjuvant treatment planning.

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Upper GI & Pancreatic

Fistula Risk Score (FRS)

Fistula Risk Score predicts clinically relevant pancreatic fistula after pancreaticoduodenectomy to guide intraoperative drain placement decisions.

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Upper GI & Pancreatic

MSKCC Gastric Cancer Nomogram

MSKCC Gastric Cancer Nomogram estimates disease-specific survival after R0 gastrectomy to guide adjuvant chemotherapy decisions in gastric cancer.

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Upper GI & Pancreatic

JGCA Risk Classifier (EGC Curability)

JGCA criteria classify early gastric cancer endoscopic resection curability to determine if additional surgical gastrectomy is required.

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GI, GIST & Peritoneal

Modified Glasgow Prognostic Score (mGPS)

Modified Glasgow Prognostic Score uses CRP and albumin to assess inflammation-based cancer prognosis and guide supportive care planning.

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Universal / General Oncology

Glasgow Prognostic Score (Standard)

Glasgow Prognostic Score combines CRP and albumin to assess systemic inflammation and estimate cancer prognosis for treatment planning.

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GI, GIST & Peritoneal

Fong Clinical Risk Score (CRS)

Fong Clinical Risk Score predicts recurrence after hepatic resection of colorectal liver metastases to guide postoperative surveillance planning.

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GI, GIST & Peritoneal

Peritoneal Carcinomatosis Index (PCI)

Peritoneal Carcinomatosis Index quantifies tumor burden across 13 abdominal regions to evaluate candidacy for cytoreductive surgery and HIPEC.

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GI, GIST & Peritoneal

NIH GIST Risk (Miettinen)

NIH GIST risk classification stratifies gastrointestinal stromal tumors by size and mitotic count to guide adjuvant imatinib therapy decisions.

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GI, GIST & Peritoneal

AFIP GIST Risk (Miettinen)

AFIP Miettinen criteria stratify GIST progression risk by tumor size, mitotic rate, and anatomic location to guide surveillance and treatment.

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GI, GIST & Peritoneal

Oncotype DX® Colon Recurrence Score

Oncotype DX Colon Recurrence Score estimates recurrence risk in stage II/III colon cancer to guide adjuvant chemotherapy decision-making.

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GI, GIST & Peritoneal

Stage II Colon Cancer Risk Assessment

Stage II Colon Cancer Risk Assessment identifies high-risk pathologic features to guide adjuvant chemotherapy decisions per NCCN and ASCO guidelines.

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GI, GIST & Peritoneal

PSDSS (Prostate Cancer-Specific Survival)

PSDSS stratifies survival in colorectal peritoneal metastases using symptoms, PCI, and histology to assess cytoreductive surgery candidacy.

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Lung Cancer & IO

GRIm Score

GRIm Score predicts overall survival on immune checkpoint inhibitors using albumin, LDH, and NLR to select immunotherapy candidates.

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Lung Cancer & IO

LIPI Score (Lung Immune)

LIPI Score stratifies metastatic NSCLC patients by dNLR and LDH to predict immunotherapy response and guide checkpoint inhibitor decisions.

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Lung Cancer & IO

Lung-RADS™ v2022

Lung-RADS v2022 categorizes pulmonary nodules on screening CT to standardize lung cancer risk assessment and guide follow-up intervals.

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Lung & Thoracic Oncology

Small Cell Lung Cancer Staging (VALSG)

VALSG staging classifies Small Cell Lung Cancer as limited or extensive stage to determine eligibility for curative chemoradiation.

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Lung & Thoracic Oncology

Solitary Pulmonary Nodule Malignancy Risk (Mayo)

Mayo Clinic model calculates malignancy probability for solitary pulmonary nodules to guide decisions on biopsy, resection, or CT surveillance.

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Lung & Thoracic Oncology

Herder Model (Pulmonary Nodule)

Herder Model estimates malignancy probability in solitary pulmonary nodules using PET-CT results to guide biopsy or surveillance decisions.

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Lung & Thoracic Oncology

Brock (PanCan) Nodule Risk

Brock PanCan model estimates lung cancer probability in pulmonary nodules detected on CT to guide biopsy versus surveillance decisions.

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Lung & Thoracic Oncology

PLCOm2012 Lung Cancer Risk

PLCOm2012 model estimates 6-year lung cancer risk in ever-smokers to determine eligibility for low-dose CT screening per NCCN guidelines.

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Lung & Thoracic Oncology

Masaoka-Koga Staging (Thymoma)

Masaoka-Koga staging classifies thymoma invasion depth to guide surgical resection planning and adjuvant therapy decisions in thymic tumors.

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Lung & Thoracic Oncology

Mesothelioma EORTC Prognostic Index

EORTC Prognostic Index predicts survival in malignant pleural mesothelioma to guide decisions on multimodal therapy versus supportive care.

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Lung & Thoracic Oncology

Mesothelioma CALGB Score

CALGB Mesothelioma Score stratifies malignant pleural mesothelioma prognosis to guide treatment intensity and clinical trial eligibility.

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Neuro-Oncology

WHO CNS Tumor Grade (2021)

WHO 2021 CNS Tumor Grading classifies central nervous system tumors into grades 1-4 using histology and molecular markers to guide treatment.

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Neuro-Oncology

RPA (Brain Metastases)

RTOG RPA classifies brain metastases patients into prognostic groups by age, KPS, and disease status to guide radiation treatment planning.

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Neuro-Oncology

GPA (Graded Prognostic Assessment)

Graded Prognostic Assessment estimates median survival in brain metastases patients to guide whole-brain radiotherapy or surgical decisions.

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Neuro-Oncology

Diagnosis-Specific GPA (Brain Mets)

Diagnosis-Specific GPA estimates survival in brain metastases from Lung, Breast, Melanoma, Renal, or GI primaries to guide radiation treatment planning.

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Bone & Spine Metastases

Tokuhashi Score Calculator — Spine Metastases Surgical Prognosis

Calculate the revised Tokuhashi score for spinal metastases prognosis. Evaluate 6 prognostic parameters to guide surgical decision-making for vertebral metastatic disease.

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Bone & Spine Metastases

Tomita Score (Spine Mets)

Tomita Score evaluates spinal metastases prognosis based on tumor grade and metastatic burden to guide surgical treatment strategy.

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Bone & Spine Metastases

SINS (Spinal Instability)

SINS quantifies spinal instability from metastatic tumors using six clinical and radiographic factors to guide surgical consultation decisions.

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Bone & Spine Metastases

NESMS (Epidural Spinal Cord)

NESMS predicts 1-year survival after surgical decompression for spinal metastases to guide operative versus palliative management decisions.

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Bone & Spine Metastases

Mirels Score (Fracture Risk)

Mirels Score predicts pathologic fracture risk in metastatic long bone lesions to guide prophylactic surgical fixation versus radiotherapy.

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Bone & Spine Metastases

Bauer Score (Bone Mets)

Bauer score estimates survival in spinal metastases patients to guide surgical versus palliative treatment decisions for bone metastases.

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Bone & Spine Metastases

Katagiri Score (Bone Mets)

Katagiri score predicts survival in patients with skeletal metastases to guide palliative versus curative surgical intervention decisions.

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Sarcoma

FNCLCC Grade (Soft Tissue Sarcoma)

FNCLCC Grading assigns soft tissue sarcoma histologic grade based on differentiation, mitotic count, and necrosis to predict metastatic risk.

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Sarcoma

Enneking Staging (Bone/Sarcoma)

Enneking Staging classifies musculoskeletal sarcomas by grade, compartment, and metastasis to determine surgical resection margins.

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Histiocytic Disorders

HLH-2004 Diagnostic Criteria Calculator — Hemophagocytic Lymphohistiocytosis

Apply the HLH-2004 diagnostic criteria (5 of 8 criteria) for hemophagocytic lymphohistiocytosis. Systematic evaluation tool based on the Histiocyte Society diagnostic guidelines.

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Histiocytic Disorders

HScore for HLH

HScore calculates the probability of hemophagocytic lymphohistiocytosis (HLH) diagnosis to guide initiation of immunosuppressive therapy.

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Histiocytic Disorders

LCH Risk Organ Classification

LCH Risk Organ Classification stratifies Langerhans cell histiocytosis by system involvement to guide treatment intensity decisions.

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Histiocytic Disorders

Ann Arbor Staging (Histiocytic Sarcoma)

Ann Arbor staging classifies histiocytic sarcoma extent by nodal and extranodal involvement to guide treatment between localized and systemic.

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Endocrine Tumors

Weiss Score (Adrenal)

Weiss Score evaluates nine histologic criteria to differentiate benign adrenocortical adenoma from malignant adrenocortical carcinoma.

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Endocrine Tumors

PASS Score (Pheochromocytoma)

PASS Score differentiates benign from malignant pheochromocytoma using 12 histological features to guide adrenal tumor management decisions.

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Endocrine Tumors

NET Grade / WHO 2019

WHO 2019 NET grading classifies neuroendocrine tumors by Ki-67 index and mitotic count to guide treatment selection and prognosis estimation.

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Supportive Care & Emergencies

MASCC Risk Index

MASCC Risk Index identifies low-risk febrile neutropenia patients in oncology to guide outpatient versus inpatient management decisions.

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Supportive Care & Emergencies

CARG Toxicity Score (Geriatric)

CARG Toxicity Score predicts Grade 3-5 chemotherapy toxicity risk in older adults (≥65y) to guide treatment intensity decisions in geriatric oncology.

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Supportive Care & Emergencies

G8 Screening Tool

G8 Geriatric Oncology Screening — quick 8-item assessment to identify elderly cancer patients needing comprehensive geriatric evaluation.

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Supportive Care & Emergencies

CISNE Score (Febrile Neutropenia)

CISNE score predicts serious complications in apparently stable febrile neutropenia to identify cancer patients safe for outpatient management.

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Pain & Palliative

Opioid Rotation & OME Calculator

Opioid Rotation Calculator performs evidence-based equianalgesic conversion with NCCN safety protocols for cancer pain management and dose adjustment.

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Pain & Palliative

ESAS-R Calculator — Edmonton Symptom Assessment System Revised

ESAS-R (Edmonton Symptom Assessment System Revised) calculator for palliative care. Assess 10 common cancer symptoms including pain, fatigue, nausea, and anxiety on a 0-10 scale.

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Pain & Palliative

PaP Score (Palliative Prognosis)

PaP Score predicts 30-day survival probability in advanced cancer palliative care patients to stratify end-of-life treatment intensity.

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Pain & Palliative

Palliative Prognostic Index (PPI)

Palliative Prognostic Index predicts weeks-to-months survival in terminal cancer patients using clinical symptoms without blood tests.

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Hematology

NCCN-IPI (Lymphoma)

NCCN-IPI stratifies diffuse large B-cell lymphoma into four prognostic risk groups to guide rituximab-era chemoimmunotherapy treatment intensity.

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Hematology

CLL-IPI

CLL-IPI stratifies 5-year overall survival in Chronic Lymphocytic Leukemia using TP53, IGHV, beta-2 microglobulin, stage, and age to guide therapy.

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Hematology

MIPI (Mantle Cell Lymphoma)

MIPI calculates prognosis in advanced mantle cell lymphoma using age, ECOG, LDH, and WBC to guide treatment intensity and trial selection.

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Hematology

IPS (Hodgkin Lymphoma)

IPS (Hasenclever) predicts progression-free survival in advanced Hodgkin lymphoma to guide escalation of first-line chemotherapy regimens.

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Hematology

IPS-7 (Adult Hodgkin Lymphoma)

International Prognostic Score (IPS-7) for advanced Hodgkin lymphoma — 7-factor risk stratification to guide ABVD vs intensified regimens.

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Hematology

CHIPS (Childhood Hodgkin Score)

CHIPS score stratifies pediatric Hodgkin Lymphoma risk to guide treatment intensification or de-escalation based on stage, bulk, and B-symptoms.

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Hematology

DIPSS (Myelofibrosis)

DIPSS estimates survival in Primary Myelofibrosis at any disease timepoint using age, blood counts, blasts, and symptoms to guide transplant decisions.

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Hematology

DIPSS-Plus (Myelofibrosis)

DIPSS-Plus refines Primary Myelofibrosis prognosis by adding karyotype, platelet count, and transfusion status to stratify transplant candidacy.

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Hematology

IPSSWM (Waldenström)

IPSSWM stratifies Waldenstrom macroglobulinemia patients into prognostic risk groups to guide initiation of chemoimmunotherapy treatment.

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Hematology

IPSET-Thrombosis (Essential Thrombocythemia)

IPSET-Thrombosis score stratifies thrombotic risk in essential thrombocythemia patients to guide aspirin and cytoreductive therapy decisions.

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Hematology

ELTS Score (CML)

ELTS Score estimates long-term CML-specific survival risk in chronic myeloid leukemia patients on TKI therapy to guide treatment intensity.

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Hematology

SANZ Risk Score (APL)

Sanz Risk Score stratifies APL patients by WBC and platelet count to guide ATRA-based treatment intensity in Acute Promyelocytic Leukemia.

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Hematology

HCT-CI (Transplant Risk)

HCT-CI (Sorror Score) quantifies comorbidity burden to stratify non-relapse mortality risk before allogeneic hematopoietic cell transplantation.

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Hematology

R-ISS (Multiple Myeloma)

R-ISS stages newly diagnosed multiple myeloma using albumin, beta-2 microglobulin, LDH, and cytogenetics to stratify 5-year survival prognosis.

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Hematology

FLIPI (Follicular Lymphoma)

FLIPI predicts overall survival in follicular lymphoma using five prognostic factors to stratify patients into low, intermediate, or high risk.

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Hematology

IPSS-R for MDS

IPSS-R stratifies myelodysplastic syndrome patients by survival and AML transformation risk to guide transplant and treatment timing.

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Hematology

International Prognostic Index (IPI)

International Prognostic Index predicts overall survival in diffuse large B-cell lymphoma to guide R-CHOP chemotherapy intensity decisions.

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Liver / HCC

ALBI Score

ALBI score grades hepatocellular carcinoma liver function using albumin and bilirubin levels to stratify prognosis and guide HCC treatment.

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Liver / HCC

ALBI-T Score

ALBI-T score combines liver function grade with tumor TNM stage to stratify hepatocellular carcinoma prognosis and guide treatment selection.

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Liver / HCC

BCLC Staging System (2022 Update)

BCLC 2022 staging classifies hepatocellular carcinoma by tumor burden, liver function, and performance status to guide HCC treatment strategy.

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Liver / HCC

HKLC Staging System

HKLC staging classifies hepatocellular carcinoma patients into treatment groups to guide resection, TACE, or systemic therapy selection.

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Liver / HCC

CNLC Staging (China)

CNLC staging classifies hepatocellular carcinoma by tumor extent, liver function, and performance status to guide resection, TACE, or systemic therapy.

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Liver / HCC

JIS Score (Japan Integrated Staging)

JIS score integrates Child-Pugh liver function and Japanese TNM stage to stratify survival prognosis in hepatocellular carcinoma patients.

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Liver / HCC

Child-Pugh Score

Child-Pugh Score classifies cirrhosis severity into Class A, B, or C to estimate survival and guide liver transplant or hepatic surgery decisions.

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Liver / HCC

MELD Score

MELD Score calculates end-stage liver disease severity using bilirubin, creatinine, and INR to prioritize patients for liver transplantation.

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Liver / HCC

Milan Criteria

Milan Criteria evaluate HCC tumor burden to determine liver transplant eligibility and guide treatment selection for hepatocellular carcinoma.

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Liver / HCC

CLIP Score

CLIP score estimates hepatocellular carcinoma survival by integrating Child-Pugh stage, tumor morphology, AFP, and portal vein thrombosis status.

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Liver / HCC

LI-RADS® v2018 (CT/MRI)

LI-RADS v2018 classifies liver observations on CT/MRI to estimate HCC probability and guide diagnostic workup in at-risk patients.

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Kidney / Renal

IMDC (Heng) Risk Criteria Calculator — Metastatic Renal Cell Carcinoma

Calculate the IMDC/Heng risk score for metastatic renal cell carcinoma. Evaluate 6 prognostic factors to classify patients as favourable, intermediate, or poor risk for first-line therapy selection.

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Kidney / Renal

MSKCC (Motzer) Score

MSKCC (Motzer) Score stratifies metastatic renal cell carcinoma into risk groups to guide first-line systemic therapy selection for mRCC patients.

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Kidney / Renal

Leibovich Score (RCC)

Leibovich Score predicts metastasis-free survival after nephrectomy for clear cell renal cell carcinoma to guide surveillance planning.

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Kidney / Renal

SSIGN Score (Mayo)

SSIGN Score predicts cancer-specific survival in clear cell renal cell carcinoma using pathologic stage, tumor size, nuclear grade, and necrosis.

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Kidney / Renal

UISS (UCLA Integrated Staging)

UISS stratifies localized renal cell carcinoma into risk groups using TNM stage, Fuhrman grade, and ECOG to predict post-nephrectomy survival.

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Breast Cancer

BI-RADS Score (Breast)

BI-RADS classifies breast imaging findings into risk categories to standardize reporting and guide biopsy or surveillance management decisions.

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Breast Cancer

Nottingham Prognostic Index (NPI)

Nottingham Prognostic Index calculates invasive breast cancer prognosis using tumor size, grade, and nodal status to guide adjuvant therapy.

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Breast Cancer

MSKCC DCIS Nomogram — Breast Cancer DCIS Recurrence Risk Calculator

Calculate DCIS recurrence risk using the Memorial Sloan Kettering (MSKCC) nomogram. Estimate 5 and 10-year local recurrence probability after breast-conserving surgery for ductal carcinoma in situ.

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Breast Cancer

Van Nuys Prognostic Index (USC-VNPI)

Van Nuys Prognostic Index (VNPI) — evidence-based DCIS scoring for treatment decisions: excision alone, excision + radiation, or mastectomy.

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Breast Cancer

CPS+EG Score

CPS+EG score estimates distant metastasis-free survival in breast cancer after neoadjuvant chemotherapy to stratify post-treatment prognosis.

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Breast Cancer

Allred Score for ER/PR

Allred score quantifies ER and PR hormone receptor staining in breast cancer to determine endocrine therapy eligibility and predict response.

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Breast Cancer

Magee Equation (Est. Oncotype DX®)

Magee Equation estimates Oncotype DX Recurrence Score from standard breast cancer pathology to guide decisions on genomic testing need.

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Breast Cancer

AJCC Prognostic Stage (Breast)

AJCC 8th edition breast cancer staging integrates anatomic TNM with ER, PR, HER2, and grade to classify prognostic stage and guide therapy.

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Breast Cancer

Residual Cancer Burden (RCB)

Residual Cancer Burden score quantifies remaining breast tumor after neoadjuvant chemotherapy to classify pathologic response and guide adjuvant care.

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Breast Cancer

PREDICT Breast (Prognostic Index)

PREDICT Breast estimates survival benefit of adjuvant chemotherapy, endocrine therapy, and trastuzumab in early invasive breast cancer.

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Breast Cancer

Gail Model (Relative Risk)

Gail Model estimates 5-year and lifetime relative risk of invasive breast cancer to identify candidates for chemoprevention with tamoxifen.

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Breast Cancer

Oncotype DX Recurrence Score Calculator — Breast Cancer Genomic Risk

Interpret your Oncotype DX 21-gene recurrence score for HR+/HER2- breast cancer. Understand risk category and chemotherapy benefit based on TAILORx and RxPONDER trial evidence.

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Breast Cancer

MammaPrint Interpreter

MammaPrint Interpreter classifies 70-gene breast cancer assay results to guide chemotherapy de-escalation decisions per MINDACT trial data.

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Breast Cancer

Prosigna / PAM50 Interpreter

Prosigna PAM50 interprets Risk of Recurrence score to stratify 10-year distant recurrence risk in HR+/HER2- early-stage breast cancer.

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Breast Cancer

EndoPredict (EPclin) Interpreter

EndoPredict EPclin Score stratifies early and late distant recurrence risk in ER+/HER2- breast cancer to guide chemotherapy decisions.

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Breast Cancer

Breast Cancer Index (BCI)

Breast Cancer Index predicts late distant recurrence risk and evaluates benefit of extending endocrine therapy beyond 5 years in HR+ breast cancer.

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Prostate Cancer

D'Amico Risk Classification

D'Amico classification stratifies localized prostate cancer into Low, Intermediate, or High risk using PSA, Gleason, and stage to guide treatment.

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Prostate Cancer

Epstein Criteria (Insignificant Cancer)

Epstein Criteria evaluate PSA density, Gleason score, and core data to identify clinically insignificant prostate cancer for active surveillance.

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Prostate Cancer

PI-RADS™ v2.1 (Prostate MRI)

PI-RADS v2.1 stratifies prostate MRI lesions by likelihood of clinically significant cancer to guide biopsy decision-making in urology.

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Prostate Cancer

Gleason Score & ISUP Grade

Gleason Score calculator converts primary and secondary biopsy patterns into ISUP Grade Groups to stratify prostate cancer aggressiveness.

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Prostate Cancer

CAPRA Score

CAPRA score predicts prostate cancer recurrence after radical prostatectomy using PSA, Gleason, and stage to stratify pre-operative risk.

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Prostate Cancer

CAPRA-S Score (Post-Surgical)

CAPRA-S score predicts biochemical recurrence after radical prostatectomy using pathologic data to guide adjuvant prostate cancer treatment.

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Prostate Cancer

Decipher® Prostate Risk

Decipher Genomic Classifier interprets the 22-gene prostate cancer score to predict metastasis risk and guide adjuvant or salvage radiotherapy decisions.

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Prostate Cancer

Prolaris® (CCP Score)

Prolaris CCP Score assesses prostate cancer aggressiveness via cell cycle gene expression to guide active surveillance or treatment decisions.

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Prostate Cancer

Oncotype DX® GPS (Prostate)

Oncotype DX GPS assesses prostate cancer genomic aggressiveness to guide active surveillance versus definitive treatment decisions.

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Prostate Cancer

ProMark® Proteomic Score

ProMark proteomic assay predicts aggressive pathology risk in prostate cancer biopsies to support active surveillance versus treatment decisions.

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Bladder / Urothelial

EORTC NMIBC Risk Calculator — Bladder Cancer Recurrence & Progression

Calculate non-muscle invasive bladder cancer (NMIBC) recurrence and progression risk using the EORTC scoring system. Evidence-based risk stratification for clinical decision-making.

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Bladder / Urothelial

CUETO Risk Score (BCG-Treated)

CUETO score predicts 5-year recurrence and progression risk in non-muscle invasive bladder cancer patients treated with BCG immunotherapy.

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Bladder / Urothelial

EAU NMIBC Risk Stratification (2024)

EAU NMIBC Risk Stratification classifies bladder cancer into Low to Very High risk groups to guide BCG therapy and cystectomy decisions.

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Testicular & Germ Cell Tumors

IGCCCG Risk Classification (2021 Update)

IGCCCG classification stratifies metastatic germ cell tumors into risk groups to guide platinum-based chemotherapy regimen selection.

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Testicular & Germ Cell Tumors

MSKCC Stage I NSGCT Nomogram

MSKCC NSGCT Nomogram predicts occult retroperitoneal metastasis risk in clinical stage I non-seminoma to guide surveillance versus RPLND decisions.

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Gynecologic Oncology

FIGO GTN Risk Score

FIGO GTN Risk Score stratifies gestational trophoblastic neoplasia into low or high risk to guide single-agent vs multi-agent chemotherapy.

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Gynecologic Oncology

RMI (Risk of Malignancy Index)

Risk of Malignancy Index estimates ovarian cancer probability in adnexal masses using CA125, ultrasound, and menopausal status for triage.

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Gynecologic Oncology

ROMA Score (Ovarian)

ROMA score combines HE4 and CA125 biomarkers with menopausal status to stratify ovarian malignancy risk and guide surgical referral decisions.

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Gynecologic Oncology

AGO Score (DESKTOP)

AGO DESKTOP score predicts complete resection likelihood in recurrent ovarian cancer to guide secondary cytoreductive surgery decisions.

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Gynecologic Oncology

iMODEL (Ovarian Recurrence)

iMODEL Score — predict complete cytoreduction (R0) probability in platinum-sensitive recurrent ovarian cancer. 6-factor risk model.

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Gynecologic Oncology

O-RADS Calculator — Ovarian-Adnexal Reporting & Data System (Ultrasound)

O-RADS ultrasound calculator for ovarian and adnexal mass risk stratification. Classify lesions from O-RADS 1 (normal) to O-RADS 5 (high risk) based on ACR criteria.

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Gynecologic Oncology

ESGO/ESTRO/ESP Endometrial Risk (2021)

ESMO 2021 Risk Classification stratifies endometrial cancer by stage, grade, and LVSI to guide adjuvant radiotherapy and chemotherapy decisions.

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Gynecologic Oncology

Mayo Criteria (Endometrial)

Mayo Criteria predict lymph node metastasis risk in endometrial cancer to guide surgical staging and lymphadenectomy decision-making.

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Gynecologic Oncology

Sedlis Criteria (Cervical)

Sedlis Criteria evaluate intermediate-risk cervical cancer patients after hysterectomy to determine the need for adjuvant pelvic radiation therapy.

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Gynecologic Oncology

Moore Criteria (Advanced Cervical)

Moore Criteria predict survival in recurrent or metastatic cervical cancer to guide cisplatin-based chemotherapy regimen selection decisions.

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Skin Cancer

Sentinel Lymph Node Risk (Melanoma)

Estimates sentinel lymph node positivity risk in melanoma based on Breslow depth, ulceration, and age to guide biopsy decision-making.

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Thyroid Cancer

MACIS Score (Thyroid)

MACIS Score estimates 20-year cause-specific survival in papillary thyroid carcinoma to guide postoperative risk stratification decisions.

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Thyroid Cancer

ATA Risk Stratification (Thyroid)

ATA risk stratification classifies differentiated thyroid cancer recurrence risk to guide post-surgical surveillance and TSH suppression targets.

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About OncoToolkit: Your Comprehensive Oncology Calculator Resource

OncoToolkit provides healthcare professionals with a comprehensive suite of evidence-based oncology calculators, staging systems, and prognostic tools. Our platform supports clinical decision-making across all major cancer types, from initial diagnosis through treatment planning and follow-up care.

Comprehensive Cancer Staging & Prognosis Tools

Access validated scoring systems including ECOG and Karnofsky Performance Status for functional assessment, Child-Pugh and ALBI scores for liver function evaluation, and tumor-specific staging calculators following AJCC/UICC guidelines. Our tools cover breast cancer (Oncotype DX, NPI), prostate cancer (Gleason, CAPRA), lung cancer (TNM staging, GPA), and many more.

Treatment Decision Support

Make informed treatment decisions with calculators designed to assess treatment eligibility, predict response, and evaluate toxicity risk. From chemotherapy dosing based on BSA calculations to immunotherapy eligibility assessment, our tools help optimize patient outcomes while minimizing adverse events.

Evidence-Based Clinical Tools

Every calculator on OncoToolkit is based on peer-reviewed research and validated in clinical practice. We provide transparent methodology with references to original publications, ensuring you understand the evidence behind each tool. Explore our oncology glossary for terminology definitions and video tutorials about how to use this app.

OncoToolkit is for educational and clinical decision support purposes only. Always verify results with current clinical guidelines and institutional protocols.