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DIPSS (Myelofibrosis)
Clinical Context & Background
The DIPSS estimates survival in patients with Primary Myelofibrosis. Unlike the IPSS (used at diagnosis), DIPSS can be used at any time during the disease course. It evaluates Age, White Blood Cell count, Hemoglobin, Peripheral Blasts, and Constitutional Symptoms.
Formula Logic
Sum of points (0-6). Hb < 10 gets 2 points, others 1 point.Reference Data
| Risk Group | Score | Median Survival |
|---|---|---|
| Low | 0 | Not Reached (15+ years) |
| Intermediate-1 | 1 - 2 | 14.2 years |
| Intermediate-2 | 3 - 4 | 4 years |
| High | 5 - 6 | 1.5 years |
Evidence-based oncology decision support. Verify with clinical guidelines.