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SSIGN Score (Mayo)
Clinical Context & Background
The SSIGN (Stage, Size, Grade, and Necrosis) score from the Mayo Clinic predicts cancer-specific survival in patients with clear cell renal cell carcinoma (ccRCC). It is commonly used for both localized and metastatic patients to estimate long-term outcomes.
Formula Logic
Sum of points derived from Stage, Size, Grade, and Necrosis.Reference Data
| SSIGN Score | 5-Year Cancer Specific Survival |
|---|---|
| 0 - 2 | 97 - 99% |
| 3 - 4 | 89 - 95% |
| 5 - 6 | 77 - 85% |
| 7 - 9 | 42 - 62% |
| ≥ 10 | 18 - 25% |
Evidence-based oncology decision support. Verify with clinical guidelines.