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Mesothelioma CALGB Score

Clinical Context & Background

The CALGB prognostic score for malignant pleural mesothelioma uses distinct clinical variables compared to EORTC, including pleural LDH, platelets, chest pain, and age. It stratifies patients into six prognostic subgroups.
Primary Source EvidenceHerndon JE, et al. Factors predictive of survival among 337 patients with mesothelioma treated with chemotherapy at Cancer and Leukemia Group B institutions. Chest. 1998;113(3):723-731.
Formula Logic
Based on Age, Histology, PS, Chest Pain, Platelets, LDH, Hb.

Reference Data

Risk GroupMedian Survival
Group 113.9 months
Group 210.5 months
Group 3 - 47 - 9 months
Group 5 - 61.4 - 4 months

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