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D'Amico Risk Classification
Clinical Context & Background
The D'Amico classification system stratifies patients with localized prostate cancer into three risk groups (Low, Intermediate, High) based on PSA, Gleason Score, and Clinical Stage. It predicts the risk of biochemical recurrence after localized treatment.
Formula Logic
Risk group determined by the worst feature present.Reference Data
| Risk Group | Definition | 5-Year PSA Failure Risk |
|---|---|---|
| Low Risk | PSA ≤10 AND Gleason ≤6 AND T1-T2a | < 10-20% |
| Intermediate Risk | PSA 10-20 OR Gleason 7 OR T2b | 20-40% |
| High Risk | PSA >20 OR Gleason ≥8 OR ≥T2c | > 50% |
Related Tools
Evidence-based oncology decision support. Verify with clinical guidelines.