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HomeDIPSS-Plus (Myelofibrosis)
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DIPSS-Plus (Myelofibrosis)

Clinical Context & Background

The DIPSS-Plus incorporates three additional independent prognostic factors (low platelet count, transfusion need, and unfavorable karyotype) into the original DIPSS model to improve risk stratification in Primary Myelofibrosis.
Primary Source EvidenceGangat N, Caramazza D, Vaidya R, et al. DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status. J Clin Oncol. 2011;29(4):392-397.
Formula Logic
DIPSS Score + Points for Platelets <100, Transfusion, and Unfavorable Karyotype.

Reference Data

Risk GroupTotal ScoreMedian Survival
Low015.4 years
Intermediate-116.5 years
Intermediate-22 - 32.9 years
High≥ 41.3 years

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