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Clinical calculator summary

JIS Score (Japan Integrated Staging)

The Japan Integrated Staging (JIS) score integrates liver function (Child-Pugh) and tumor stage (LCSGJ TNM) into a single prognostic score.

Evidence-based context for fast calculator use

Purpose:
JIS score integrates Child-Pugh liver function and Japanese TNM stage to stratify survival prognosis in hepatocellular carcinoma patients.
Population:
patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment
Factors:
Child-Pugh Grade, LCSGJ TNM Stage
Reference:
Kudo M, Chung H, Osaki Y. Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a new proposed staging system, the Japan Integrated Staging Score (JIS score). J Gastroenterol. 2003;38(3):207-215.
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JIS Score (Japan Integrated Staging)

Clinical Context & Background

The Japan Integrated Staging (JIS) score integrates liver function (Child-Pugh) and tumor stage (LCSGJ TNM) into a single prognostic score. It has been shown to stratify survival better than the CLIP score in some cohorts.
Primary Source EvidenceKudo M, Chung H, Osaki Y. Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a new proposed staging system, the Japan Integrated Staging Score (JIS score). J Gastroenterol. 2003;38(3):207-215.
Formula Logic
JIS Score = Child-Pugh Score (0-2) + TNM Score (0-3). Range 0-5.

Reference Data

JIS Score10-Year Survival Rate
065%
140%
220%
310%
4 - 5< 5%

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • Use JIS Score (Japan Integrated Staging) when jIS score integrates Child-Pugh liver function and Japanese TNM stage to stratify survival prognosis in hepatocellular carcinoma patients.
  • Confirm that the patient, diagnosis, disease phase, and available inputs match the cited model before calculation.

How To Interpret

  • Interpret the displayed result using the calculator-specific formula and reference table, spanning 0 through 4 - 5.
  • A boundary result should prompt input verification and clinical review rather than false precision.

What To Do Next

  • Integrate liver reserve, portal hypertension, tumor burden, vascular invasion, extrahepatic disease, performance status, and transplant policy.
  • Document the inputs, result, timing, and clinical context so the assessment can be reproduced.

Limitations

  • Liver function, HCC stage, imaging category, and transplant criteria are complementary but not interchangeable.
  • The result supports clinician judgment and does not independently determine treatment.

Validated Population

patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment

How to apply this result

For a representative case, verify Child-Pugh Grade, LCSGJ TNM Stage, calculate the result, and confirm that its classification matches the highlighted reference band before continuing the disease-specific pathway.

Liver / HCC hubContinue to related calculators and clinical workflow resources.

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Frequently Asked Questions

When should JIS Score (Japan Integrated Staging) be used?

Use it for patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment when all required inputs and the intended clinical setting are confirmed.

Can JIS Score (Japan Integrated Staging) determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.