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Clinical calculator summary

Original conventional JIS score

An additive 0-5 HCC score combining Child-Turcotte-Pugh class and LCSGJ fourth-edition TNM stage.

Evidence-based context for fast calculator use

Purpose:
Support historical baseline prognostic stratification in established hepatocellular carcinoma.
Population:
Patients with established HCC and independently assigned Child-Turcotte-Pugh class and LCSGJ fourth-edition TNM stage.
Factors:
Child-Turcotte-Pugh class, LCSGJ fourth-edition TNM stage
Reference:
Kudo M, Chung H, Osaki Y. J Gastroenterol. 2003;38:207-215. DOI 10.1007/s005350300038.
HomeOriginal 2003 Japan Integrated Staging (JIS) Score
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Original 2003 Japan Integrated Staging (JIS) Score

Use the original JIS only for established hepatocellular carcinoma; do not substitute another liver-tumor diagnosis.

Clinical Context & Background

The original conventional Japan Integrated Staging score described by Kudo, Chung, and Osaki in 2003 adds Child-Turcotte-Pugh class points to Liver Cancer Study Group of Japan fourth-edition TNM stage points. It is a historical baseline prognostic stratification for established hepatocellular carcinoma.
The calculator does not derive either upstream classification. LCSGJ fourth-edition TNM must be assigned using that edition's historical definitions and must not be substituted with, or translated from, AJCC/UICC or a later LCSGJ edition. Modified JIS, biomarker-combined JIS, ALBI-T, and mALBI-T are separate models.
Formula Logic
Conventional JIS = Child-Turcotte-Pugh points (A=0, B=1, C=2) + LCSGJ fourth-edition TNM points (I=0, II=1, III=2, IV=3). Range 0-5.

Reference Data

JIS totalSource arithmeticInterpretation boundary
0Child-Pugh 0 + TNM 0Historical score only
1Components sum to 1Historical score only
2Components sum to 2Historical score only
3Components sum to 3Historical score only
4Components sum to 4Historical score only
5Child-Pugh 2 + TNM 3Historical score only

Clinical Workflow

Use, Interpret, And Continue The Patient Pathway

Expand for workflow guidance, limitations, examples, and related next steps.

When To Use

  • At baseline for established hepatocellular carcinoma when both required source classifications are already assigned.
  • Only when the tumor stage is specifically LCSGJ fourth edition.

How To Interpret

  • The total is an integer from 0 to 5; higher scores represented worse historical prognosis in the source cohorts.
  • Stage IV includes LCSGJ fourth-edition stages IV-A and IV-B.

What To Do Next

  • Interpret the historical score alongside current multidisciplinary staging, liver-function assessment, and contemporary guidance.

Limitations

  • Does not calculate Child-Turcotte-Pugh class or LCSGJ TNM stage.
  • Do not substitute AJCC/UICC TNM, a later LCSGJ edition, modified JIS, biomarker JIS, ALBI-T, or mALBI-T.
  • Not applicable to cholangiocarcinoma, combined liver tumors, or liver metastases.
  • Does not provide an individualized survival probability or determine treatment, transplant, or resection eligibility.

Validated Population

Historical Japanese cohorts with established HCC classified using the conventional 2003 JIS specification.

Calculation verification history

Verified
  1. : Production browser revalidation

    • Three source-backed JIS cases passed through visible production controls at scores 0, 3, and 5.
    • No unexpected N/A, literal undefined value, stale control, unsupported risk gauge, or browser-console error was observed.
    Download latest production check (Excel)

    Case-level evidence is retained in validation/browser-revalidation/Japan-Integrated-Staging-2026-08-03.json.

  2. : Production browser validation

    • Ten source-backed cases were exercised on the public production route through visible browser controls; 10/10 case records passed their expected-versus-observed assertions across 11 visible submissions.
    • Overall browser status: failed-console. medium: Production emitted minified React error #418 during route loads/reloads used by this run.
    • Case-level inputs, expected and observed results, reset/repeat behavior, failure reproductions, and console evidence are retained in the production-browser evidence record.

    Case-level production evidence is retained in validation/browser-production/Japan-Integrated-Staging.json.

  3. : Input workflow simplified and revalidated

    • Reduced the public form to result-, branch-, unit-, and applicability-changing inputs; removed or consolidated non-scoring, administrative, and duplicate questions.
    • Preserved the verified calculation or report-interpretation logic, thresholds, model version, component logic, and supported result pathways behind strict deterministic adapters.
    • Passed the calculator-specific regression audit, adapter-parity and malformed-input checks, the 144-calculator input-quality audit, and the 43-calculator entry-burden audit.
  4. : Full validation test

    • 240/240 source-table, arithmetic, invalid-input, UI/reset, applicability, trace, safety, registry, report, and isolation checks passed with zero score mismatch.
    • This verifies source-to-code implementation of the original conventional JIS score; it is not independent clinical validation, individualized prognosis, or treatment advice.
  5. : Calculation and input-contract correction

    • Locked the calculator to the original 2003 conventional JIS using independently assigned Child-Turcotte-Pugh class and LCSGJ fourth-edition TNM stage.
    • Added an established-HCC applicability gate and strict semantic inputs; removed favorable defaults, numeric coercion, malformed-value fallthrough, and extra-field acceptance.
    • Removed invented prognosis groups and unsupported survival percentages, and clarified that Stage IV includes LCSGJ IV-A and IV-B without accepting those strings as alternate inputs.

    Included in the current validation report.

Verification confirms the calculator implementation against the cited model; it is not independent clinical validation, regulatory approval, or medical advice.

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Frequently Asked Questions

When should Original 2003 Japan Integrated Staging (JIS) Score be used?

Use it for patients undergoing liver-function, hepatocellular carcinoma staging, imaging, or transplant assessment when all required inputs and the intended clinical setting are confirmed.

Can Original 2003 Japan Integrated Staging (JIS) Score determine treatment by itself?

No. Interpret the result with the cited evidence, complete clinical assessment, current guidelines, and patient-specific goals.

Evidence-based oncology decision support. Verify with clinical guidelines.