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HomeWeiss Score (Adrenal)
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Weiss Score (Adrenal)

Clinical Context & Background

The Weiss System is the standard histological scoring system for adrenocortical tumors. It evaluates 9 microscopic features. A score of 3 or higher indicates malignancy (Adrenocortical Carcinoma).
Primary Source EvidenceWeiss LM. Comparative histologic study of 43 metastasizing and 50 nonmetastasizing adrenocortical tumors. Am J Surg Pathol. 1984;8(3):163-169.
Formula Logic
Sum of 9 histologic criteria (1 point each).

Reference Data

Total ScoreDiagnosis
0 - 2Adrenocortical Adenoma (Benign)
≥ 3Adrenocortical Carcinoma (Malignant)

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