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Epstein Criteria (Insignificant Cancer)
Clinical Context & Background
The Epstein Criteria are used to identify patients with "clinically insignificant" prostate cancer who are ideal candidates for Active Surveillance. It relies on PSA density, number of positive biopsy cores, and percentage of cancer involvement per core.
Formula Logic
Insignificant if: PSAD < 0.15, Gleason ≤ 6, < 3 positive cores, ≤ 50% cancer in any core.Reference Data
| Criteria | Result |
|---|---|
| Met All Criteria | Clinically Insignificant (Candidate for AS) |
| Failed Any Criteria | Clinically Significant (Treatment likely needed) |
Evidence-based oncology decision support. Verify with clinical guidelines.