Breast Cancer Calculators
Breast cancer decision-support references for risk assessment, external genomic-report interpretation, prognostic indices, and AJCC staging.
Breast Calculator Pathways
High-intent workflows that connect risk models, prognosis calculators, genomic assays, DCIS tools, staging, and response assessment.
Risk and screening pathway
Start with Gail/BCRAT for basic invasive breast cancer risk, then use Tyrer-Cuzick or CanRisk reference guides when family history, density, or genetic risk needs deeper modelling.
Adjuvant prognosis pathway
Use the official PREDICT v3.1 tool for initial adjuvant survival estimates, CTS5 for late recurrence after 5 years of endocrine therapy, and the Oncotype DX route only for source-specific interpretation of a final external report.
DCIS and local therapy pathway
Keep VNPI, the official MSKCC DCIS nomogram, AJCC staging references, and post-neoadjuvant RCB as separate source-specific workflows.
Risk Assessment
Breast cancer risk prediction models for screening and prevention decisions.
Genomic & Molecular
Source-specific interpreters for externally generated genomic reports; these routes do not recreate proprietary assays or make treatment decisions.
Source-specific TAILORx and RxPONDER context for a final external score
70-gene expression profile for recurrence risk
12-gene EPclin score for distant recurrence
PAM50-based risk of recurrence classification
ER/PR immunohistochemistry scoring
Prognosis & Staging
Survival prediction models, prognostic indices, neoadjuvant response assessment, and TNM staging for breast cancer.
5-10 year late distant recurrence risk after endocrine therapy
Breast-specific chemotherapy toxicity risk in older adults
Original NPI-3 postoperative pathology model
USC/VNPI for DCIS treatment planning
2013 pathology-based estimated recurrence score; not an actual genomic assay
Residual Cancer Burden after neoadjuvant therapy
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In-depth clinical guides for breast cancer risk, genomic testing, and prognosis.