PREDICT Breast v3.1 Official Tool Guide

Generate estimates at the official PREDICT Breast v3.1 website. OncoToolkit does not reproduce the PREDICT algorithm or provide an alternative result recorder.

What the official tool reports

PREDICT estimates survival after surgery for early invasive breast cancer and displays the potential survival benefit associated with selected adjuvant treatments. Its output includes:

• survival with surgery only;
• the displayed contribution associated with each selected treatment;
• survival with all selected treatments;
• survival if breast-cancer death were excluded; and
• death from other causes.

Component effects are combination-dependent. Do not add the displayed component benefits independently; use the official combined-treatment output.

Supported scope

The documented source population is women aged 25-85 with early invasive breast cancer after surgery, before adjuvant treatment, and without distant metastases. DCIS and LCIS alone are outside scope.

Post-neoadjuvant and bilateral cases require particular caution because model inputs and transportability may not match an individual patient’s clinical situation. Check the current official instructions and disclaimers before use.

Interpretation boundary

PREDICT reports population estimates based on outcomes in similar women. The values are not patient-specific certainty and do not determine treatment. OncoToolkit does not:

• execute PREDICT coefficients;
• estimate an output absent from the official result;
• convert between PREDICT versions;
• sum component benefits;
• infer extended-endocrine benefit; or
• recommend treatment.

The official PREDICT site and clinical team remain the source for generating and interpreting the result.

Sources

1. Official PREDICT Breast v3.1 tool.
2. PREDICT Breast overview.
3. Official disclaimer.
4. Official algorithm information.
5. Official technical information.
6. Winton Centre PREDICT v3 R package and MIT license.
7. PREDICT v3 development and validation publication, PMCID PMC10789872.
8. Comparative validation of PREDICT v3.1 and v2.2, PMID 41991871.

This page is a clinical reference to the official tool. It is not an independent implementation or validation of PREDICT.