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HomeLeibovich-Score-Rechner - Nierenzellkarzinom
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Leibovich-Score-Rechner - Nierenzellkarzinom

cm

Clinical Context & Background

Das Modell gilt für sporadisches, unilaterales pT1-4 N0/+ M0 klarzelliges Nierenzellkarzinom nach Nephrektomie. Es verwendet TNM 2002 und den Fuhrman-Kerngrad und ist nicht das Leibovich-Modell 2018.
Referenz: Leibovich BC et al. Cancer. 2003;97(7):1663-1671. DOI: 10.1002/cncr.11234.
Formula Logic
Punkte für pT + pN + Tumorgröße + Fuhrman-Grad + Nekrose.

Reference Data

RisikogruppePunkte5-Jahres-MFS10-Jahres-MFS
Niedrig0-297,1 %92,5 %
Intermediär3-573,8 %64,3 %
Hoch≥631,2 %23,6 %

Calculation verification history

Verified
  1. : Production browser revalidation

    • Three source-backed cases passed through visible production controls at Leibovich scores 0, 3, and 11.
    • Low, Intermediate, and High groups rendered as expected.
    • No unexpected N/A, literal undefined value, stale control, unsupported gauge, or browser-console error was observed.
    Download latest production check (Excel)

    Case-level evidence is retained in validation/browser-revalidation/leibovich-prognostic-rcc-2026-08-03.json.

  2. : Production browser validation

    • Ten source-backed cases were exercised on the public production route through visible browser controls; 10/10 case records passed their expected-versus-observed assertions across 11 visible submissions.
    • Overall browser status: failed-console. medium: Production emitted minified React error #418 during route loads/reloads used by this run.
    • Case-level inputs, expected and observed results, reset/repeat behavior, failure reproductions, and console evidence are retained in the production-browser evidence record.

    Case-level production evidence is retained in validation/browser-production/leibovich-prognostic-rcc.json.

  3. : Full validation test

    • Passed 48/48 literal checks covering scores 0-11, every source category and boundary, and strict missing or invalid input behavior with zero difference.
  4. : Correction

    • Corrected pT4 to 4 points rather than 5.
    • Corrected source-group 5-year metastasis-free survival estimates to 97.1%, 73.8%, and 31.2%, and added the 10-year estimates 92.5%, 64.3%, and 23.6%.
    • Added a required positive numeric tumor-size input and rejected missing, extra, malformed, and out-of-domain inputs.

    Included in the current validation report.

Verification confirms the calculator implementation against the cited model; it is not independent clinical validation, regulatory approval, or medical advice.

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